Identification and quantification of herbal medicines
Our scientists can accurately identify and measure the active chemical constituents of six key herbal medicines, based mainly on European Pharmacopoeia (EP) methods:
- Black Cohosh Cimicifuga racemosa
- Echinacea Echinacea purpurea
- Milk Thistle Silybum marianum
- Chasteberry Agnus castus
- Passionflower Passiflora incarnata
- St John’s Wort Hypericum perforatum.
Using advanced chromatography to identify active markers and mass spectrometry to quantify the trace amounts, our process ensures the safety and efficacy of the active ingredients in your herbal medicine product.
State of the art instruments
We use the state-of-the-art CAMAG® HPTLC System or advanced High-Performance Thin-Layer Chromatography (HPTLC) to confirm and identify the herbal substance in the sample. HPTLC is a powerful tool for rapidly comparing several samples in parallel, checking for adulteration, monitoring purity and stability, and quantifying marker compounds. The end result from the CAMAG is a unique chromatographic fingerprint based on UV colour spectra.
Once the herb has been correctly identified with the known active plant markers using advanced HPTLC, it under goes a potency assessment using mass spectrometry, specifically Liquid Chromatography Mass Spectrometry (LCMS-MS). The sophisticated instrument produces a peaks for both the sample and the comparative standard which are proportional to the concentration present. A calibration curve is prepared and this is used to calculate the exact concentration of the actives in the sample – as low as parts per billion, even parts per trillion!
Our findings are then used to help standardise the production of your herbal medicines and ensure consistency in dosage and potency for batch release testing.
Key benefits of working with ADACT
The key benefits of ADACT’s herbal medicines analytical testing are:
- UK-based laboratory with state-of-the-art analytical instruments.
- Herbal knowledge and expertise.
- ISO/IEC 17025:2017 accreditation working towards Good Manufacturing Practice (GMP).
- Fast results and turnaround – in ten working days.
Related links: https://adactmedical.com/black-cohosh-testing/
Call our expert, friendly team today
To discuss herbal medicines testing, please phone +44(0)1302 986 088 or email [email protected].
We look forward to hearing from you soon.